The diagnostic approach to a dermatological problem sometimes requires taking a biopsy, with the aim of histopathological confirmation. A skin biopsy is a simple procedure that however requires good knowledge and correct technique on the part of the dermatologist.
How is a biopsy of a skin lesion or rash performed?
The biopsy site is carefully selected and local antisepsis and anesthesia are applied. The biopsy can be performed with a round knife with a diameter of up to 6mm (Punch biopsy) or surgically, while in each case sutures are placed at the incision site. The sutures are removed at the time indicated by the dermatologist, while the material obtained is sent to the histopathologist. The material can be sent for immunohistochemistry, immunofluorescence or even for molecular testing depending on what is required for the diagnosis of the problem.